Pyrazolo-pyrrolopyridine-dione derivatives useful in the...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/14 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2756810

The present invention relates to substituted pyrazolo-pyrrolo-pyridine-dione compounds of formula (I) and meth-ods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted pyrazolo-pyrrolo-pyridine-dione compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds or pharmaceutical compositions to subjects in need thereof.

La présente invention porte sur des composés pyrazolo-pyrrolopyridine-dione substitués de formule (I) et sur des procédés de synthèse de ces composés. La présente invention porte également sur des compositions pharmaceutiques contenant des composés pyrazolo-pyrrolopyridine-dione substitués et sur des procédés de traitement de troubles prolifératifs cellulaires, tels que le cancer, par l'administration de ces composés ou de ces compositions pharmaceutiques à des sujets qui en ont besoin.

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