Scutellaria barbata extract and combinations for the...

A - Human Necessities – 61 – K

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A61K 36/539 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2706326

An extract of Scutellaria barbata D. Don is effective in the arrest of cancer cell growth in the G1 phase, the induction of apoptosis in cancer cells and the shrinking of solid cancers. The extract may be prepared as a pharmaceutical composition for administration to mammals for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers. The extract is obtained from Scutellaria barbata D. Don by contacting aerial portions of a plant from the species Scutellaria barbata D. Don with an aqueous or alcoholic solvent.

Selon l'invention, un extrait de Scutellaria barbata D. Don est efficace pour stopper la croissance de cellules cancéreuses en phase G1, pour induire l'apoptose de cellules cancéreuses et pour réduire la taille des tumeurs cancéreuses solides. L'extrait peut être préparé sous la forme d'une composition pharmaceutique destinée à être administrée à des mammifères pour le traitement de cancers solides tels que les cancers épithéliaux. Ces cancers épithéliaux comprennent le cancer du sein et le cancer de l'ovaire. L'extrait est obtenu à partir de Scutellaria barbata D. Don en mettant les parties aériennes d'une plante de l'espèceScutellaria barbata D. Don en contact avec un solvant aqueux ou alcoolique.

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