Novel preparation and administration form comprising an...

Details Novel preparation and administration form comprising an... Novel preparation and administration form comprising an...

A - Human Necessities

61

K

A61K 31/4439 (2006.01) A61K 9/16 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2376202

Novel administration forms and preparations for acid-labile active compounds are described. The novel administration forms contain individual active compound units, the active compound being present in the active compound units in a matrix made of a mixture comprising at least one fatty alcohol and at least one solid paraffin, in a matrix made of a mixture of a triglyceride and at least one solid paraffin or in a matrix made of a mixture comprising at least one fatty acid ester and at least one solid paraffin. In particular, the active compound units are microspheres which can be produced by prilling.

L'invention concerne des formes galéniques pour composés actifs acido-labiles et des préparations de ceux-ci. Ces formes galéniques comprennent des unités de composés actifs individuels, le composé actif étant présent dans les unités de composés actifs dans une matrice constituée d'un mélange comprenant au moins un alcool gras et au moins une paraffine solide, dans une matrice constituée d'un mélange d'un triglycéride et au moins une paraffine solide ou dans une matrice constituée d'un mélange comportant au moins un ester d'acide gras et au moins une paraffine solide. Plus particulièrement, les unités de composés actifs sont des microsphères pouvant être produites par grelonage.

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