Spiroindolinone derivatives

Details Spiroindolinone derivatives Spiroindolinone derivatives

C - Chemistry, Metallurgy

07

D

C07D 487/20 (2006.01) A61K 31/53 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2687160

There are provided spiroindolinone derivatives of the formula (I) and pharmaceutically acceptable salts and esters thereof, wherein X, R1, R2, R3, R4 and R are as herein described. The compounds of the present invention are useful in the treatment or control of cell proliferative disorders, in particular oncological disorders.

Dérivés de spiroindolinone représentés par la formule (I) ainsi que des sels et des esters de qualité pharmaceutique de ces dérivés. Dans cette formule, X, R1, R2, R3, R4 et R sont comme définis dans le descriptif. Les composés de l'invention conviennent pour le traitement ou le contrôle de troubles prolifératifs, en particulier de troubles oncologiques

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