Probin tyrosine kinase (pyk2) its cdna cloning and its uses

Details Probin tyrosine kinase (pyk2) its cdna cloning and its uses Probin tyrosine kinase (pyk2) its cdna cloning and its uses

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 1/14 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2207581

The present invention features a method for treatment of an organism having a disease or condition characterized by an abnormality in a signal transduction pathway, wherein the signal transduction pathway includes a PYK2 protein. The invention also features methods for diagnosing such diseases and for screening for agents that will be useful in treating such diseases. The invention also features purified and/or isolated nucleic acid encoding a PYK2 protein.

Procédé de traitement d'un organisme atteint d'une maladie ou présentant un état pathologique caractérisé par une anomalie dans la voie de transduction des signaux, ladite voie de transduction des signaux comportant une protéine PYK2. La présente invention concerne également des procédés permettant de diagnostiquer ces maladies et de rechercher des agents utiles dans le traitement de ces maladies. Elle concerne également de l'acide nucléique purifié et/ou isolé codant une protéine PYK2.

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