C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) C07K 14/395 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2272989
The present invention discloses novel telomerase-associated proteins as well as methods for isolating the genes encoding telomerase-associated proteins. Using novel screening methods presented additional telomerase-associated genes may be isolated and their protein products expressed and characterized. Identification of protein-protein interactions required for the in vivo function of telomerase provides the basis for a novel screening method for anti-tumor agents.
L'invention concerne de nouvelles protéines associées à la télomérase, ainsi que des procédés servant à isoler les gènes codant ces protéines. De nouveaux procédés de criblage permettent d'isoler des gènes supplémentaires associés à la télomérase, d'exprimer et de caractériser leurs produits de protéines. L'identification d'interactions entre protéines nécessaires au fonctionnement in vivo de la télomérase constitue la base d'un nouveau procédé de criblage afin de rechercher des agents anti-tumeur.
Baylor College Of Medicine
Swabey Ogilvy Renault
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