Ocular treatment using cyclosporin-a derivatives

Details Ocular treatment using cyclosporin-a derivatives Ocular treatment using cyclosporin-a derivatives

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61P 27/04 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2369457

A method of treating a disorder in an eye, for example, an aqueous deficient dry eye state, phacoanaphylactic endophthalmitis, or uveitis, is provided. The method generally includes administering a therapeutically effective amount of a certain cyclosporin A derivative topically to the affected eye. The derivative may be administered as a solution, suspension or ointment in a pharmaceutically acceptable excipient.

L'invention concerne une méthode de traitement d'un trouble au niveau de l'oeil, notamment un état d'oeil sec dû à un manque de sécrétions lacrymales, l'endophtalmie phaco-anaphylactique ou l'uvéite. Ladite méthode consiste, de manière générale, à administrer topiquement, sur l'oeil affecté, une dose thérapeutiquement efficace d'un certain dérivé de cyclosporine A. Ce dérivé peut être administré sous la forme d'une solution, d'une suspension ou d'un onguent incorporé dans un excipient pharmaceutiquement acceptable.

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