Compositions useful for reducing nephrotoxicity and methods...

Details Compositions useful for reducing nephrotoxicity and methods... Compositions useful for reducing nephrotoxicity and methods...

A - Human Necessities

61

K

A61K 47/40 (2006.01) A61K 31/519 (2006.01) A61K 31/704 (2006.01) A61K 33/24 (2006.01)

Patent

CA 2631014

The present invention provides compositions and methods to reduce renal damage caused by nephrotoxic drugs. The invention provides compositions comprising an anionically substituted oligosaccharide, a nephrotoxic drug and a pharmaceutically acceptable carrier, where the oligosaccharide is present in an amount effective for substantially inhibiting the nephrotoxic effect of the drug.

Compositions et procédés permettant de réduire les dégâts rénaux engendrés par des médicaments néphrotoxiques. On décrit des compositions qui renferment un oligosaccharide à substitution anionique, un médicament néphrotoxique et un vecteur pharmaceutiquement acceptable, sachant que l'oligosaccharide est présent en quantité efficace pour inhiber sensiblement l'effet néphrotoxique du médicament.

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