Treatment of cachexia

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/135 (2006.01) A61K 31/138 (2006.01) A61K 31/4704 (2006.01) A61K 31/535 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2671622

The present invention provides a means for prevention and treatment of cachexia and other chronic illnesses including but not limited to the promotion of weight gain, reduction or prevention of weight loss by administration of a substance that both reduces the sensitivity of beta-adrenergic receptors and of 5-HTla receptors. (S)- pindolol, (S)-propranolol, tertatolol or bopindolol are preferred for this purpose.

La présente invention concerne un moyen permettant de prévenir et de traiter la cachexie et d'autres maladies chroniques y compris, mais sans que ce soit limitatif, la promotion d'un gain de poids, la diminution ou la prévention d'une perte de poids par l'administration d'une substance qui réduit à la fois la sensibilité des récepteurs bêta-adrénergiques et des récepteurs 5-HT1A. A cette fin, le (S)- pindolol, le (S)-propranolol, le tertatolol ou le bopindolol sont préférés.

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