Protein-nucleic acid probes and immunoassays using same

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Details

G01N 33/543 (2006.01) C07H 19/06 (2006.01) C07H 21/00 (2006.01) C07K 16/00 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/532 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2081455

2081455 9117442 PCTABS00008 In one aspect of this invention, various protein/nucleic acid hybrid probes are described which can be used to amplify the detectable signal in immunoassays. The protein moiety is capable of functioning either as an antibody or an antigen. The nucleic acid moiety serves as a signal amplifier. In another aspect, various methods of amplifying the detectable signal in immunoassays by use of the hybrid probes and related polynucleotide probes are disclosed.

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