Indoleacetic acid and indenacetic acid derivatives as...

Details Indoleacetic acid and indenacetic acid derivatives as... Indoleacetic acid and indenacetic acid derivatives as...

A - Human Necessities

61

K

A61K 31/405 (2006.01)

Patent

CA 2562783

The presently disclosed subject matter provides derivatives of non~steroidal anti-inflammatory drugs (NSAIDs) that are characterized by substantially reduced cyclooxygenase inhibiting activity, yet retain the ability to interact with and modulate the activities of other polypeptides such as the class of peroxisome proliferators-activated receptors (PPARs) and .gamma.-~secretase. Also provided are methods of using the derivatives to treat pathological disorders.

L'invention concerne des dérivés de médicaments anti-inflammatoires non stéroïdes à inhibition de cyclo-oxygénase sensiblement réduite, mais à capacité d'interaction intacte avec les activités d'autres polypeptides - et à modulation intacte sur ces activités - du type classe de récepteurs activés par les proliférateurs de péroxysome et ?-secrétase. L'invention concerne aussi des procédés relatifs à l'utilisation des dérivés pour le traitement de troubles pathologiques.

Affiliated with

Also associated with

Rating

Indoleacetic acid and indenacetic acid derivatives as... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indoleacetic acid and indenacetic acid derivatives as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indoleacetic acid and indenacetic acid derivatives as... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2057753