C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) C07K 16/00 (2006.01) C07K 16/46 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2511967
The present invention relates to a method for the generation of immunoglobulin molecules of predetermined specificity. In particular, the invention relates to a method for the retargeting of the epitope binding specificity of one or more antibodies using single variable domains which exhibit a dominant epitope binding specificity.
La présente invention porte sur un procédé de génération de molécules d'immunoglobuline d'une spécificité prédéfinie. L'invention porte notamment sur un procédé de reciblage de la spécificité de la liaison de l'épitope d'un ou plusieurs anticorps utilisant des domaines uniques variables qui présentent une spécificité de la liaison de l'épitope dominant.
Ignatovich Olga
Tomlinson Ian
Winter Greg
Domantis Limited
Mbm Intellectual Property Law Llp
LandOfFree
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