Stable ophthalmic solution comprising latanoprost as active...

A - Human Necessities – 61 – K

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A61K 31/5575 (2006.01) A61K 9/00 (2006.01) A61K 9/08 (2006.01) A61K 47/16 (2006.01) A61P 27/06 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2496540

It is intended to provide latanoprost eye drops which can be stored at room temperature and have a high safety. Namely, eye drops containing latanoprost as the active ingredient wherein latanoprost is stabilized by at least one means selected from the following means 1) and 2) so that it can be stored at room temperature: 1) means of adjusting the pH value to 5.0 to 6.25; and 2) means of adding .epsilon.-aminocaproic acid.

L'invention concerne des gouttes ophtalmiques contenant du latanoprost qui peuvent être stockées à la température ambiante et offrent une grande sécurité. Ces gouttes ophtalmiques contiennent, comme principe actif, du latanoprost qui est stabilisé, de sorte qu'il peut être stocké à la température ambiante, selon au moins un des deux procédés suivant: ajustement du pH à 5,0-6,25; addition d'acide .epsilon.-aminocaproique.

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