Fat-trapping composition comprising an indigestible cationic...

A - Human Necessities – 61 – K

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Details

A61K 31/722 (2006.01) A61K 31/683 (2006.01) A61K 31/685 (2006.01) A61K 31/715 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2644585

The present invention relates to a composition for trapping lipids or fats, thereby preventing their degradation and their absorption in the digestive tract. The fat-trapping composition of the invention comprises an edible but indigestible cationic polysaccharide (preferably chitosan) and at least one emulsifying agent (preferably a phosphoglyceride such as lecithin), associating in the stomach and forming in the intestine a matrix for entrapping fat. Further, the present invention relates to methods for treating obesity, for reducing absorption of dietary fat and for treating and/or reducing hypertriglyceridemia, by orally administering the fat-trapping composition of the invention.

La présente invention concerne une composition servant à piéger les lipides ou les matières grasses, ce qui empêche de cette manière leur décomposition et leur absorption dans l'appareil digestif. La composition piégeant les matières grasses de l'invention comprend un polysaccharide cationique comestible mais non digestible (de préférence le chitosan) et au moins un agent émulsifiant (de préférence un phosphoglycéride tel que la lécithine), s'associant dans l'estomac et formant dans l'intestin une matrice servant à piéger la matière grasse. En outre, la présente invention concerne des procédés servant à traiter l'obésité, à réduire l'absorption de matière grasse alimentaire et à traiter et/ou réduire l'hypertriglycéridémie, en administrant oralement la composition piégeant les matières grasses de l'invention.

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