Methods and kits for detecting germ cell genomic instability

Details Methods and kits for detecting germ cell genomic instability Methods and kits for detecting germ cell genomic instability

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2584741

Disclosed are methods for detecting microsatellite instability in the germ line of males, methods of assessing risk for developing testicular cancer, methods of evaluating the microsatellite stability of putative cancer or precancerous cells or a tumor, methods for evaluating germ cells for exposure to mutagens, and kits for use in the methods of the invention.

Cette invention concerne des procédés permettant de détecter une instabilité microsatellitaire dans la lignée germinale de mâles, des procédés permettant d'évaluer le risque de développer un cancer des testicules, des procédés permettant d'évaluer la stabilité microsatellitaire de cellules cancéreuses ou précancéreuses putatives ou d'une tumeur, des procédés permettant d'évaluer des cellules germinales exposées à des mutagènes, ainsi que des nécessaires destinés à être utilisés dans les procédés de cette invention.

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