Collagen hydrogel methods

Details Collagen hydrogel methods Collagen hydrogel methods

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61F 2/14 (2006.01) A61L 27/26 (2006.01) B29D 11/00 (2006.01) G02B 1/04 (2006.01) A61F 2/16 (2006.01)

Patent

CA 2104113

2104113 9214420 PCTABS00015 A collagen-hydrogel material, artificial lens (60) or contact lens (60) for the eye (40) fabricated from the collagen-hydrogel, which, when affixed to Bowman's membrane (48), promotes and supports epithelial cell growth (52) enabling corneal epithelium, during the healing process, to attach to and cover the lens (60) and to regenerate the stroma (50) which grows over the edge of and attaches to the optical lens (60). The collagen-hydrogel is a hydrogel polymer formed by the free radical polymerization of a hydrophilic monomer solution gelled and crosslinked in the presence of an aqueous stock solution of collagen to form a three dimensional polymeric meshwork for anchoring collagen. The collagen-hydrogel material has a ratio by weight of collagen-to-hydrogel in the range of about .6-to-1000 and less than .6-to-1000 but at a level wherein sufficient collagen is present by weight to at least one of promote epithelial cell growth (52) and regeneration of the stroma (50).

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