Process for preparing trovafloxacin acid salts

Details Process for preparing trovafloxacin acid salts Process for preparing trovafloxacin acid salts

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) C07D 209/52 (2006.01)

Patent

CA 2281244

Trovafloxacin acid salts are prepared via the hydrolysis of imine intermediates using mineral acid including, but not limited to, methanesulfonic acid, ethanesulfonic acid, benzenesulfonic acid, nitric acid, sulfuric acid, phosphoric acid, hydrochloric acid, hydrobromic acid, tartaric acid, citric acid, acetic acid, and maleic acid. Trovafloxacin acid salts are useful as antibiotic agents.

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