Ribozyme inhibition of bcr-abl gene expression

Details Ribozyme inhibition of bcr-abl gene expression Ribozyme inhibition of bcr-abl gene expression

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 31/70 (2006.01) A61K 35/28 (2006.01) A61K 48/00 (2006.01) C07K 14/82 (2006.01) C12N 1/21 (2006.01) C12N 5/08 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2092571

2092571 9303141 PCTABS00019 Ribozymes effective to inhibit bcr-abl expression and the use of ribozymes to block proliferation of leukemia carrying the bcr-abl gene are disclosed. E. Coli transfected with the requisite ribozyme gene provides significant quantities thereof.

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