Solid active compound preparations

Details Solid active compound preparations Solid active compound preparations

A - Human Necessities

61

K

A61K 9/20 (2006.01)

Patent

CA 2211033

Solid preparations obtainable by the melt extrusion of A) at least one active agent, B) a mixture of B1) 10 to 90 wt.% of a water--soluble, thermoplastic polymer and B2) 10 to 90 wt.% of a low- substituted hydroxypropyl cellulose and C) 0 to 50 wt.% in relation to the total quantity of the preparation of common pharmaceutical auxiliaries.

La présente invention concerne des préparations solides qui s'obtiennent par extrusion à l'état de fusion de A) au moins un constituant actif, B) un mélange comprenant B1) de 10 à 90 % en poids d'un polymère thermoplastique soluble dans l'eau, B2) de 10 à 90 % en poids d'une hydroxypropylcellulose faiblement substituée, et C) de 0 à 50 % en poids, par rapport au poids total de la préparation, de produits auxiliaires pharmaceutiques usuels.

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