C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 31/517 (2006.01) A61P 25/24 (2006.01)
Patent
CA 2534785
Compounds of the Formula (I): and pharmaceutically acceptable salts thereof, wherein m, R1, R2, R3 R4 and R6 are as defined herein. The invention also provides methods for preparing, compositions comprising the compounds of Formula (I), as well as their uses for the manufacture of medicaments useful in the treatment of diseases such as phobias, stress-related illnesses, mood disorders, eating disorders, generalized anxiety disorders, stress-induced gastrointestinal dysfunctions, neurodegenerative diseases, and neuropsychiatric disorders.
L'invention concerne des composés de formule (I) et des sels correspondants acceptables pharmaceutiquement, m, R?1¿, R?2¿, R?3¿, R?4¿ et R?6¿ y étant définis tels que mentionnés. Cette invention a aussi trait à des procédés de préparation de compositions contenant les composés de formule (I), ainsi qu'à leurs utilisations dans l'élaboration de médicaments utilisés dans le traitement de maladies, telles que les phobies, les troubles liés au stress, les troubles de l'humeur, les troubles de l'alimentation, les troubles d'anxiété généralisés, les dysfonctionnements gastro-intestinaux induits par le stress, les maladies neurodégénératives et les troubles neuropsychiatriques.
Clark Robin Douglas
Cournoyer Richard Leo
O'yang Counde
Borden Ladner Gervais Llp
F.hoffmann-La Roche Ag
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