Scutellaria barbata extract for the treatment of cancer

A - Human Necessities – 61 – K

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A61K 36/539 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2629638

An extract of Scutellaria barbata D. Don is effective in the arrest of cancer cell growth in the Gl phase, the induction of apoptosis in cancer cells and the shrinking of solid cancers. The extract may be prepared as a pharmaceutical composition for administration to mammals for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers. The extract is obtained from Scutellaria barbata D. Don by contacting aerial portions of a plant from the species Scutellaria barbata D. Don with an aqueous or alcoholic solvent.

La présente invention concerne un extrait de Scutellaria barbata, D. Don, efficace dans l~arrêt de la croissance de cellules cancéreuses en phase G1, l~induction de l~apoptose de cellules cancéreuses et la réduction de tumeurs solides. L~extrait peut être préparé de la même façon qu~une composition pharmaceutique destinée à être administrée à des mammifères dans le traitement de tumeurs solides, tels que des cancers épithéliaux. De tels cancers épithéliaux incluent le cancer du sein et des cancers ovariens. L~extrait est obtenu à partir de la Scutellaria barbata D.Don, en mettant en contact des parties aéricoles d~une plante de l~espèce Scutellaria barbata D. Don avec un solvant aqueux ou alcoolique.

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