Methods for detecting cancer and monitoring cancer progression

G - Physics – 01 – N

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G01N 33/68 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2528253

Mutant BNIP3 plays a functionally important role in the development of solid tumors and in resistance to chemotherapy and radiation treatments. The invention relates to methods of detecting cancer, methods of monitoring the progression of cancer, methods of identifying patients with cancer that is resistant to chemotherapy or radiation treatments, and diagnostic kits for performing the methods of the invention.

Sachant que le BNIP3 mutant joue un rôle fonctionnel important dans le développement de tumeurs solides et la résistance à la chimiothérapie et aux traitements par rayonnement, l'invention concerne des procédés de détection de cancer, des procédés de contrôle de progression de cancer, des procédés d'identification de patients atteints de cancer résistant à la chimiothérapie ou aux traitements par rayonnement, et des kits de diagnostic pour la mise en oeuvre des procédés considérés

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