A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 29/08 (2006.01) A61L 29/10 (2006.01) A61L 29/14 (2006.01) A61L 29/16 (2006.01) A61L 31/08 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2679727
According to an aspect of the invention, medical devices are provided which include a substrate, at least one porous reservoir containing at least one therapeutic agent disposed over the substrate, at least one nanoporous layer disposed over the at least one porous reservoir, and at least one plugged aperture, which may be located within the substrate, within the nanoporous layer, or both. According to another aspect of the invention, a method of forming a medical device is provided which includes (a) forming a porous reservoir over a substrate, (b) forming a nanoporous layer over the porous reservoir, (c) forming an aperture within the substrate or the nanoporous layer, (d) filling the porous reservoir with therapeutic agent through the aperture, and (d) plugging the aperture.
L'invention concerne des dispositifs médicaux comprenant un substrat, au moins un réservoir poreux contenant au moins un agent thérapeutique disposé au-dessus du substrat, au moins une couche nanoporeuse disposée au-dessus du réservoir poreux, et au moins une ouverture bouchée, qui peut être située dans le substrat, dans la couche nanoporeuse, ou dans les deux. L'invention concerne également un procédé de formation d'un dispositif médical, qui comprend les étapes consistant à (a) former un réservoir poreux au-dessus d'un substrat, (b) former une couche nanoporeuse au-dessus du réservoir poreux, (c) former une ouverture dans le substrat ou dans la couche nanoporeuse, (d) remplir le réservoir poreux avec un agent thérapeutique à travers l'ouverture, et (d) boucher l'ouverture.
Atanasoska Liliana
Weber Jan
Boston Scientific Limited
Kirby Eades Gale Baker
LandOfFree
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