Rho kinase inhibitors

Details Rho kinase inhibitors Rho kinase inhibitors

C - Chemistry, Metallurgy

07

C

C07C 237/42 (2006.01) A61K 31/167 (2006.01) A61K 31/277 (2006.01) A61K 31/472 (2006.01) A61P 9/10 (2006.01) C07C 275/42 (2006.01) C07D 217/22 (2006.01)

Patent

CA 2674389

Substituted amide and urea derivatives useful as inhibitors of Rho kinase are described, which inhibitors can be useful in the treatment of various disorders such as cardiovascular diseases, cancer, neurological diseases, renal diseases, bronchial asthma, erectile dysfunction and glaucoma.

L'invention concerne des dérivés d'amide et d'urée substitués utiles comme inhibiteurs de la Rho kinase, lesquels inhibiteurs peuvent être utiles dans le traitement de divers troubles tels que les troubles cardiovasculaires, le cancer, les troubles neurologiques, les néphropathies, l'asthme, le dysfonctionnement érectile et le glaucome.

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