Chimeric interleukin-6 soluble receptor/ligand protein,...

Details Chimeric interleukin-6 soluble receptor/ligand protein,... Chimeric interleukin-6 soluble receptor/ligand protein,...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61K 38/20 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) C07K 14/54 (2006.01) C07K 14/715 (2006.01) C12N 5/10 (2006.01) C12N 15/24 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2295936

Chimeric proteins constructed from the fusion of the naturally occurring form of the soluble IL-6 receptor and IL-6 which are useful for treatment of cancer and liver disorders, enhancement of bone marrow transplantation, and treatment of other IL-6 related conditions are provided.

Ces protéines chimères obtenues grâce à la fusion de la forme d'origine naturelle du récepteur d'IL-6 soluble et d'IL-6, se révèlent efficaces en matière de thérapie anticancéreuse et de traitement de troubles hépatiques, d'amélioration de la greffe de moelle osseuse ainsi que de traitement d'autres troubles liés à l'IL-6.

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