Heterodimeric receptor libraries using phagemids

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/63 (2006.01) C07K 14/01 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 7/01 (2006.01) C12N 15/10 (2006.01) C12N 15/13 (2006.01) C12N 15/62 (2006.01) C12N 15/64 (2006.01) C12N 15/70 (2006.01) C40B 40/02 (2006.01) C40B 40/08 (2006.01) C40B 40/10 (2006.01) C40B 50/06 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2108147

The invention comprises filamentous phage encapsulating a genome encoding first and second polypeptides of an autogenously assembling heterodimeric receptor, such as an antibody, anchored to a filamentous phage coat protein membrane anchor domain. Such a phage may be used for expressing a recombinant gene product on the surface of the phage.

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