Interleukin-21 variants with altered binding to the il-21...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/435 (2006.01)

Patent

CA 2671665

The invention is concerned with IL-21 polypeptide variants having an altered binding to the common gamma chain ( c) of the IL-21 receptor and the use thereof in therapy.

L'invention porte sur des variants du polypeptide IL-21 ayant une liaison modifiée à la chaîne gamma commune (c) du récepteur de IL-21, et sur l'utilisation de ces variants en thérapie.

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