Substituted 3-aminosydnone imines, process for their...

Details Substituted 3-aminosydnone imines, process for their... Substituted 3-aminosydnone imines, process for their...

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) A61K 31/42 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2050977

23233-254 ABSTRACT The invention relates to novel substituted 3-amino- sydnone imines of the general formula I Image (I) (I) in which n denotes 0 or 1, and their pharmacologically acceptable salts and acid addition salts. The compounds possess useful pharmacological properties. For example, they are able to release nitric oxide under physiological conditions and thus to increase the antiaggregatory, antiadhesive and muscle-relaxing effect of endothelium-derived relaxing factor (EDRF). They are consequently useful for the treatment of angina pectoris and for the prevention and treatment of thromboses.

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