Recombinant infectious bovine rhinotracheitis virus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) A61K 39/265 (2006.01) A61K 39/295 (2006.01) C07K 14/06 (2006.01) C07K 14/115 (2006.01) C07K 14/14 (2006.01) C07K 14/18 (2006.01) C07K 16/08 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/38 (2006.01) C12N 15/86 (2006.01) C12N 15/869 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2113641

2113641 9302104 PCTABS00019 The present invention provides recombinant infectious bovine rhinotracheitis (IBR) viruses useful in vaccines to protect bovines from diseases particular to them, including infectious bovine rhinotracheitis and bovine respiratory disease complex. The present invention further provides methods for distinguishing an animal vaccinated with a vaccine of the present invention from an animal infected with a naturally-occurring IBR virus. The present invention also provides isolated DNA encoding the gpE glycoprotein, the gpG glycoprotein, and US2 genes of an IBR virus. The present invention further provides homology vectors for producing recombinant IBR viruses.

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