Use of catecholamines and related compounds as...

A - Human Necessities – 61 – K

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Details

A61K 31/137 (2006.01) A61K 31/216 (2006.01) A61K 31/222 (2006.01) A61K 31/36 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/522 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2675148

A catecholamine or related compound of formula (I) having (S)-configuration at .beta.-carbon and having a lipophilicity greater than (S)- noradrenalme, a physiologically tolerated salt thereof, a prodrug thereof, a physiologically functional derivative thereof or any mixture thereof is useful as an anti-angiogemc agent A catecholamine or related compound of formula (II) in which a .beta.-hydroxy group has been modified is also anti-angiogemc

L'invention concerne une catécholamine ou un composé associé de formule (I) dont le carbone ß a la configuration (S) et dont la lipophilicité est supérieure à celle de la (S)-noradrénaline, l'un de ses sels physiologiquement toléré, l'un de ses promédicaments, l'un de ses dérivés physiologiquement fonctionnel ou un mélange quelconque des composés précédents qui est utile en tant que catécholamine agent anti-angiogénique A ou un composé associé de formule (II) dont un groupe .beta.-hydroxy a été modifié, qui est également anti-angiogénique.

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