Hmg-coa reductase-inhibiting imino-substituted pyridines

C - Chemistry – Metallurgy – 07 – D

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C07D 213/55 (2006.01) A61K 31/44 (2006.01) C07D 405/06 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2022423

Abstract HMG-CoA reductase-inhibiting imino-substituted pyridines of the formula Image (I) in which R1 is optionally substituted aryl, R2 is optionally substituted aryl or alkyl, OH, alkoxy, aralkoxy, or optionally sub- stituted aryloxy, R3 is cycloalkyl, or optionally substituted aryl or alkyl, R4 is alkyl or cycloalkyl, X is -CH2-CH2- or -CH=CH-, R is Image or Image R6 is H or alkyl, and R7 is H, alkyl, phenylalkyl, aryl or a cation, and their salts. Le A 27 057

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