Non-invasive drug delivery system targeting posterior eye...

A - Human Necessities – 61 – K

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A61K 47/32 (2006.01) A61K 9/14 (2006.01) A61K 9/18 (2006.01) A61K 9/24 (2006.01) A61K 31/573 (2006.01) A61K 47/38 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2617040

Disclosed is a non-invasive delivery system for a drug administered, which has an excellent capability of drug transfer into the posterior eye tissue via a local eye tissue. A solid composition comprising a drug to be delivered and a mucosa-adhesive substance having an adhesion strength to the drug of 200 to 1000 g can be administered to the conjunctival sac. Thus, a drug delivery system can be constructed which has an excellent capability of drug transfer into the posterior eye tissue via a local eye tissue.

L~invention propose un système non invasif pour administrer un médicament, ayant une excellente capacité de transfert du médicament dans un tissu postérieur de l'AEil à travers un tissu local de l'AEil. Une composition solide qui comprend un médicament à délivrer et une substance adhésive à la muqueuse ayant une force d'adhésion au médicament de 200 à 1000 g peut être administrée dans le sac conjunctival. Ainsi, un système d'administration de médicament ayant une excellente capacité de transfert du médicament dans le tissu postérieur de l'AEil à travers un tissu local de l'AEil peut être obtenu.

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