Synthesis of n-acetyl neuraminic acid derivatives

Details Synthesis of n-acetyl neuraminic acid derivatives Synthesis of n-acetyl neuraminic acid derivatives

C - Chemistry, Metallurgy

07

H

C07H 7/033 (2006.01) C07D 309/28 (2006.01)

Patent

CA 2144342

A method for the preparation of 5-acetamido-2,3,4,5-tetradeoxy-4-guanidino-D- glycero-D-galacto-non-2-eno-pyranosonic acid by reaction of 5-acetamido-2,3,4,5-tetradeoxy-4-amino-D-glycero-D-galacto- non-2-eno-pyranosonic acid with pyrazole-IH- carboxamidine or a derivative thereof in aqueous medium.

L'invention concerne un procédé de préparation de l'acide 5-acétamido-2,3,4,5-tétradésoxy-4-guanidino-D_-glycéro-D_-galacto-non-2-éno-pyranosonique par réaction en milieu aqueux de l'acide 5-acétamido-2,3,4,5-tétradésoxy-4-amino-D_-glycéro-D_-galacto-non-2-éno-pyranosonique avec la pyrazole-1H-carboxamidine ou un dérivé de celle-ci.

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