Proliferation antagonistic inhibitor of mesenchymal cells

Details Proliferation antagonistic inhibitor of mesenchymal cells Proliferation antagonistic inhibitor of mesenchymal cells

A - Human Necessities

61

K

A61K 31/70 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2175368

The invention provides an antagonistic inhibitor of the prolifertion of mesenchymal cells, which contains the AP-1 nucleotide comprising TGAGTCA or TGACTCA which is a part of a gene promoter, as a therapeutic agent of collagen diseases including rheumatoid arthritis.

L'invention concerne un inhibiteur antagoniste de la croissance des cellules mésenchymateuses, qui peut être utilisé pour traiter les maladies du collagène typifiées par la polyarthrite rhumatoïde. Cet inhibiteur contient un nucléotide AP-1 contenant du TGAGTCA ou TGACTCA constituant un activateur d'expression des gènes.

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