Therapeutic agent for bladder irritative symptoms associated...

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01) A61P 13/08 (2006.01) A61P 13/10 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2442472

Remedies for vesical stimulation in association with prostatauxe which contain as the active ingredient tricyclic compounds represented by the following general formula (I) or pharmacologically acceptable salts thereof: (I) wherein R1 represents hydrogen, optionally substituted lower alkyl, etc.; X1-X2-X3 represents CR5=CR6-CR7=CR8, CR5=CR6-S, etc.; Y represents -CH2S-, SOCH2, etc.; and R2 represents hydrogen, etc.

L'invention concerne des remèdes de stimulation vésicale associés à une hypertrophie de la prostate, contenant, en tant que principe actif, des composés tricycliques, ou leurs sels acceptables sur le plan pharmaceutique, représentés par la formule générale (I): dans laquelle R¿1? représente un hydrogène, un groupe alkyle inférieur éventuellement substitué, X¿1?-X¿2?-X¿3? représente un groupe CR¿5?=CR¿6?-CR¿7?=CR¿8?, CR¿5?=CR¿6?-S; Y représente un groupe CH¿2?S-, SOCH¿2?, et R¿2? représente un hydrogène.

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