Influenza vaccines with reduced amounts of squalene

Details Influenza vaccines with reduced amounts of squalene Influenza vaccines with reduced amounts of squalene

A - Human Necessities

61

K

A61K 39/145 (2006.01) A61K 39/295 (2006.01) A61P 31/16 (2006.01)

Patent

CA 2751379

Influenza vaccines include hemagglutinin from at least one influenza A virus strain and at least one influenza B virus strain. They also include an oil-in-water emulsion adjuvant with submicron oil droplets, comprising squalene. In some embodiments the hemagglutinin concentration is >12 µg/ml per strain. In some embodiments the squalene concentration is <19mg/ml. In some embodiments the vaccine is mercury-free. In some embodiments the vaccine has a unit dose volume between 0.2-0.3mL. In some embodiments the squalene concentration is 9.75mg/mL or 4.88mg/mL. In some embodiments the vaccine includes antigens from two influenza A virus strains and two influenza B virus strains.

L'invention concerne des vaccins contre la grippe qui comprennent de l'hémagglutinine provenant d'au moins une souche de virus de la grippe A et au moins une souche de virus de la grippe B. Ces vaccins comprennent aussi un adjuvant d'émulsion huile dans l'eau comportant des gouttelettes d'huile submicroniques, y compris du squalène. Dans certaines formes de réalisation, la concentration d'hémagglutinine est supérieure à 12µg/ml par souche. Dans certaines formes de réalisation, la concentration de squalène est inférieure à 19mg/ml. Dans certaines formes de réalisation, le vaccin est dépourvu de mercure. Dans certaines formes de réalisation, le vaccin présente un volume de dose unitaire compris entre 0,2 et 0,3ml. Dans certaines formes de réalisation, la concentration de squalène est de 9,75mg/ml ou de 4,88mg/ml. Dans certaines formes de réalisation, le vaccin comprend des antigènes provenant de deux souches du virus de la grippe A et deux souches du virus de la grippe B.

Affiliated with

Also associated with

Rating

Influenza vaccines with reduced amounts of squalene does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Influenza vaccines with reduced amounts of squalene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Influenza vaccines with reduced amounts of squalene will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2072290