Osteogenic devices and methods of use thereof for repair of...

A - Human Necessities – 61 – L

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A61L 27/54 (2006.01) A61L 27/12 (2006.01) A61L 27/22 (2006.01) A61L 31/02 (2006.01) A61L 31/04 (2006.01)

Patent

CA 2284098

Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art. Defects susceptible to repair with the instant invention include, but are not limited to critical size defects, non-critical size defects, non-union fractures, fractures, osteochondral defects, subchondral defects, and defects resulting from degenerative diseases such as osteochondritis dissecans.

L'invention concerne des dispositifs ostéogéniques améliorés et des méthodes permettant de les utiliser afin de réparer des défauts des os et des cartilages. Ces dispositifs et méthodes stimulent la formation d'un tissu de réparation ayant une meilleure stabilité, malgré l'utilisation d'une quantité moindre de protéines ostéogéniques, que les autres dispositifs du même type. Les défauts susceptibles d'être réparés par la présente invention sont, sans y être limités, les suivants: défauts de taille critiques, défauts de taille non critiques, fractures non consolidées, fractures, défauts ostéochondraux, défauts sous-chondraux et défauts résultant de maladies dégénératives telles que l'ostéochondrite disséquante.

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