A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/425 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/5575 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2472199
Methods for the treatment, prevention, or inhibition of pain, inflammation, or inflammation-related disorder, and for the treatment or inhibition of cardiovascular disease or disorder, and for the treatment or inhibition of cancer in a subject in need of such treatment, prevention, or inhibition, include treating the subject with a peroxisome proliferator activated receptor- .gamma. agonist and a cyclooxygenase-2 selective inhibitor or prodrug thereof. Compositions, pharmaceutical compositions and kits for effecting the particular methods are also described.
La présente invention concerne des procédés de traitement, prévention ou inhibition de la douleur, de l'inflammation, ou des troubles liés à l'inflammation et des procédés de traitement ou inhibition de maladies ou troubles cardio-vasculaires, ainsi que des procédés de traitement ou d'inhibition du cancer chez un sujet nécessitant ce type de traitement, prévention ou inhibition. Ces procédés consistent à traiter le sujet à l'aide d'un agoniste .gamma. du récepteur activé du proliférateur du péroxysome, et d'un inhibiteur sélectif de la cyclooxygénase-2 ou du promédicament de ce dernier. L'invention traite également de compositions, compositions pharmaceutiques et de kits pour mettre en oeuvre ces procédés.
Mcfadden Fincham
Pharmacia Corporation
LandOfFree
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