A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/404 (2006.01) A61K 31/47 (2006.01) A61K 38/17 (2006.01) A61P 9/10 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2502357
Linkage of myocardial infarction (MI) and a locus on chromosome 13q12 is disclosed. In particular, the FLAP gene within this locus is shown by genetic association analysis to be a susceptibility gene for MI. Pathway targeting for treatment and diagnostic applications in identifying those have MI or at risk of developing MI, in particular are described.
L'invention concerne le lien entre l'infarctus du myocarde et un locus sur le chromosome 13q12. Précisément, on fait apparaître par analyse d'association génétique que le gène FLAP dans ce locus est un gène de susceptibilité pour l'infarctus du myocarde. L'invention concerne en particulier le ciblage de trajet pour les applications de traitement et de diagnostic, dans l'identification des sujets atteints ou risquant d'être atteints d'un infarctus du myocarde.
Gulcher Jeffrey R.
Gurney Mark E.
Helgadottir Anna
Decode Genetics Ehf.
Smart & Biggar
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