Topical compositions containing 5'-adenosine-diphosphate ribose

Details Topical compositions containing 5'-adenosine-diphosphate ribose Topical compositions containing 5'-adenosine-diphosphate ribose

A - Human Necessities

61

K

A61K 8/60 (2006.01) A61K 8/67 (2006.01) A61Q 5/00 (2006.01) A61Q 17/04 (2006.01) A61Q 19/08 (2006.01)

Patent

CA 2612312

Disclosed are topical skin care compositions and corresponding methods of using those compositions in preventing, retarding, or treating the harmful effects of solar radiation on skin. The compositions comprise 05'-adenosine- diphosphate ribose (ADPR) and a dermatologically acceptable carrier, wherein the compositions are applied topically to the skin prior to, during, or shortly after exposure to the sun. It has been found that 05'-adenosine- diphosphate ribose is unique among many nucleoside derivatives in protecting skin cells from the harmful effects of solar radiation, especially UV radiation.

L'invention concerne des compositions topiques pour le soin de la peau et des méthodes correspondantes d'utilisation de ces compositions pour prévenir, retarder ou traiter les effets nocifs du rayonnement solaire sur la peau. Ces compositions comprennent du 05'-adénosine-diphosphate ribose (ADPR) et un support dermatologiquement acceptable, lesdites compositions étant appliquées de façon topique sur la peau avant, pendant ou juste après l'exposition au soleil. Il s'avère que le 05'-adénosine-diphosphate ribose est le seul composé parmi de nombreux dérivés nucléosidiques à protéger les cellules cutanées contre les effets nocifs du rayonnement solaire, en particulier du rayonnement UV.

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