Methods for profiling transcriptosomes

Details Methods for profiling transcriptosomes Methods for profiling transcriptosomes

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C12N 7/01 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2638904

The present invention concerns a method for profiling variations in gene transcription (e.g., variable RNA processing) from complex and/or unknown genomic regions. Rather than screening EST or cDNA libraries for transcripts of interest, the method of the invention involves the reverse, i.e., using the genetic locus responsible for the gene product as a tool to capture representatives from this (specific) region.

La présente invention concerne un procédé de profilage de variations dans la transcription de gènes (par exemple, un traitement ARN variable) à partir de régions génomiques complexes et/ou inconnues. Plutôt que le criblage de banques d~EST ou d~ADN-c pour des produits de transcription d~intérêt, le procédé de la présente invention implique le contraire, c~est-à-dire l~utilisation du locus génétique responsable du produit génétique comme outil de capture de représentants de cette région (spécifique).

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