C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/08 (2006.01) A61K 31/404 (2006.01) A61P 3/00 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2624007
The present invention relates to substituted indoles, compositions containing such compounds and methods of treatment The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus and related conditions.
La présente invention concerne des indoles substitués, des compositions contenant de tels composés et des procédés de traitement. Les composés sont des antagonistes du récepteur du glucagon et ils peuvent donc être utilisés pour traiter, pour prévenir ou pour retarder le déclenchement d'un diabète sucré de type 2 et des états apparentés.
Bittner Amy R.
Kim Ronald M.
Parmee Emma R.
Sinz Christopher Joseph
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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