Mntf peptide compositions and methods of use

A - Human Necessities – 61 – K

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Details

A61K 38/17 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01)

Patent

CA 2716392

The present invention relates to novel Motoneuronotrophic Factors (MNTF) peptides and analogs thereof, including compositions capable of promoting the growth and viability of neurons. MNTF peptides between two and six amino acids in length are provided, as well as analogs of these MNTF peptides that are modified by covalent attachment to another moiety. Other embodiments are described herein.

La présente invention concerne de nouveaux peptides de type MNTF (pour "Motoneuronotrophic Factor" ou "facteur motoneurotrophique") et certains de leurs analogues, y-compris des compositions capables de favoriser la croissance et la viabilité des neurones. L'invention concerne ainsi des peptides MNTF d'une longueur pouvant faire deux à six acides aminés, ainsi que des analogues de ces peptides MNTF, modifiés par attachement par covalence à un autre groupe fonctionnel. L'invention concerne également d'autres modes de réalisation.

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