C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/67 (2006.01) A61K 48/00 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/82 (2006.01) C12N 15/85 (2006.01) C12P 21/02 (2006.01) C12N 15/53 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2601574
The present invention provides a method of identifying a human subject having increased or decreased sensitivity to warfarin, comprising detecting in the subject the presence of a single nucleotide polymorphism in the VKOR gene, wherein the single nucleotide polymorphism is correlated with increased or decreased sensitivity to warfarin, thereby identifying the subject having increased or decreased sensitivity to warfarin.
La présente invention concerne un procédé pour l~identification d~un sujet humain ayant une sensibilité augmentée ou diminuée à la warfarine, comprenant la détection chez le sujet de la présence d~un polymorphisme d~un seul nucléotide dans le gène VKOR, le polymorphisme d~un seul nucléotide étant corrélé avec une sensibilité augmentée ou diminuée à la warfarine, identifiant de ce fait le sujet ayant une sensibilité augmentée ou diminuée à la warfarine.
Li Tao
Stafford Darrel W.
Sim & Mcburney
University Of North Carolina At Chapel Hill
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