Aqueous anaesthetic compositions comprising propofol

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/05 (2006.01) A61K 31/167 (2006.01) A61K 47/48 (2006.01) A61P 23/00 (2006.01) A61P 23/02 (2006.01)

Patent

CA 2618799

The invention discloses an aqueous anaesthetic Propofol composition that is stable, autoclave sterilized, suitable for parental administration, having reduced incidence of pain upon injection. The composition comprises propofol, 2-hydroxypropyl-.beta.-cyclodextrin and a local anaesthetic, Lignocaine.

La présente invention concerne une composition aqueuse anesthésique de propofol qui est stable, stérilisée en autoclave, adaptée à une administration parentérale et qui présente une incidence de douleur réduite lors de l'injection. Cette composition comprend du propofol, de la 2-hydroxypropyl-ß-cyclodextrine et un anesthésique local, de la lignocaïne.

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