C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/09 (2006.01) A61K 31/661 (2006.01) A61P 23/00 (2006.01) C07F 9/10 (2006.01) C07F 9/12 (2006.01)
Patent
CA 2521837
According to the invention, there is provided a phosphate derivative of a phenolic hydroxy compound comprising the reaction product of the following steps: (d) reacting the phenolic hydroxy compound with an alkyl .alpha.:.omega. dialdehyde or a sugar-like polyhydroxy dialdehyde to form a hemiacetal; (e) reducing the terminal aldehyde group on the product from step (a) to a hydroxyl group; and (f) phosphorylating the hydroxyl group formed in step (b) to produce a phosphate derivative of the phenolic hydroxy compound.
La présente invention se rapporte à un dérivé phosphaté d'un composé hydroxy phénolique comportant le produit de réaction des étapes suivantes : (d) réaction du composé hydroxy phénolique avec un dialdéhyde d'alkyle .alpha. :.omega. ou un dialdéhyde polyhydroxy de type glucide aux fins de la formation d'un hémiacétal; (e) réduction du groupe aldéhyde terminal sur le produit issu de l'étape (a) en un groupe hydroxyle ; et (f) phosphorylation du groupe hydroxyle formé au cours de l'étape (b) aux fins de la production d'un dérivé phosphaté du composé hydroxy phénolique.
Kannar David
West Simon Michael
Mcfadden Fincham
Vital Health Sciences Pty Ltd.
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