Isolated peptides derived from mage-2

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/705 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2261579

New peptides derived from the MAGE-2 molecule and which bind to HLA-A*0201 molecules are disclosed. Some of these are especially useful because, when complexed to their HLA-A*0201 partner molecules, they induce CTL proliferation.

Cette invention se rapporte à de nouveaux peptides dérivés de la molécule MAGE-2, qui se lient à des molécules HLA-A*0201. Certains de ces peptides sont particulièrement utiles du fait que, lorsqu'ils forment des complexes avec leurs molécules partenaires HLA-A*0201, ils induisent une prolifération des lymphocytes T cytolytiques.

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