Antiepileptogenic complex of albumin with docosahexaenoate

Details Antiepileptogenic complex of albumin with docosahexaenoate Antiepileptogenic complex of albumin with docosahexaenoate

A - Human Necessities

61

K

A61K 38/38 (2006.01) A61K 31/202 (2006.01) A61P 25/08 (2006.01) A61K 47/42 (2006.01)

Patent

CA 2575827

The infusion of an albumin-docosahexaenoic acid (DHA) complex was shown to inhibit the progression of kindling epileptogenesis. This was shown in trice using kindling as the experimental epilepsy model. The DHA-albumin complex was shown to affect the activity of the brain when administered intraperitoneally. This therapy could also be administered intravenously, This therapy would also be effective against chronic epilepsy.

On a pu démontrer que la perfusion d'un complexe d'albumine-acide docosahexaénoïque (DHA) permet d'inhiber la progression de l'épileptogenèse d'embrasement, chez des souris, en utilisant l'embrasement comme modèle expérimental de l'épilepsie; et que le complexe DHA-albumine influence l'activité du cerveau lorsqu'il est administré par voie intrapéritonéale. Le traitement peut aussi être administré par voie intraveineuse. Ce traitement est également efficace contre l'épilepsie chronique.

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