Neural receptor tyrosine kinase

Details Neural receptor tyrosine kinase Neural receptor tyrosine kinase

A - Human Necessities

01

K

A01K 67/027 (2006.01) C07K 14/705 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12N 15/54 (2006.01) C12Q 1/48 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2186365

Novel receptor tyrosine kinase protein and isoforms thereof which are expressed in migrating axons, and nucleic acid molecules encoding the novel protein isoforms and parts thereof are disclosed. The invention also relates to methods for identifying substances which are capable of binding to the receptor protein and methods for screening for agonists or antagonists of the binding of the protein and substance. Diagnostic and therapeutic methods using the protein and nucleic acid molecules are also described.

Nouvelle protéine de tyrosine-kinase réceptrice et isoformes de celle-ci exprimées dans les axones en migration, et molécules d'acide nucléique codant les nouvelles isoformes de cette protéine et des parties de celles-ci. On a également prévu des procédés d'identification de substances aptes à se lier à la protéine réceptrice et des procédés de dépistage d'agonistes et d'antagonistes de la liaison entre la protéine et la substance. En outre, on a prévu des procédés diagnostiques et thérapeutiques mettant en oeuvre cette protéine et les molécules d'acide nucléique.

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