C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A01K 67/027 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12N 9/22 (2006.01) C12N 15/12 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) C40B 40/06 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2414495
Polymorphic A-Kinase anchor proteins (AKAPs) and nucleic acids encoding the proteins are provided herein. Methods of detecting polymorphic AKAPs and nucleic acids encoding the AKAPs, and kits for use in the detection methods are also provided. Further provided herein are methods of identifying subjects having or at risk of developing disorders of signal transduction. Methods of determining susceptibility to morbidity and/or increased or early mortality are also provided.
L'invention concerne des protéines polymorphiques d'ancrage de la kinase A (AKAP) et des acides nucléiques codant pour ces protéines. L'invention concerne également des procédés permettant de détecter ces AKAP polymorphiques et les acides nucléiques codant pour celles-ci, ainsi que des trousses pouvant être utilisées dans ces procédés. En outre, l'invention concerne des procédés permettant d'identifier des sujets présentant ou susceptibles de développer des troubles de la transduction des signaux. L'invention concerne également des procédés permettant de déterminer la probabilité de la morbidité et/ou de l'augmentation ou de la précocité de la mortalité.
Sequenom Inc.
Smart & Biggar
LandOfFree
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